Key Publications

 

  1. Lobachevsky, P.N., Ventura, J., Giannakandropoulou, L., Forrester, H., Palazzolo, J.S., Haynes, N.M., Stevenson, A.W., Hall, C.J., Mason, J., Pollakis, G. et al. (2019) A Functional Immune System Is Required For The Systemic Genotoxic Effects Of Localised Irradiation. International Journal of Radiation Oncology*Biology*Physics, 103 1184-1193.
  2. Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N.N., Glytsou, C., Pateras, I.S., Swain, U., Souliotis, V.L. et al. (2018) Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biology, 19, 37.
  3. Ventura, J., Lobachevsky, P.N., Palazzolo, J.S., Forrester, H., Haynes, N.M., Ivashkevich, A., Stevenson, A.W., Hall, C.J., Ntargaras, A., Kotsaris, V. et al. (2017) Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses. Cancer Res, 77, 6389-6399.
  4. Pavlopoulou, A., Bagos, P.G., Koutsandrea, V. and Georgakilas, A.G. (2017) Molecular determinants of radiosensitivity in normal and tumor tissue: A bioinformatic approach. Cancer Lett, 403, 37-47. Mavragani, I., Nikitaki, Z., Souli, M., Aziz, A., Nowsheen, S., Aziz, K., Rogakou, E. and Georgakilas, A. (2017) Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis. Cancers, 9, 91.
  5. Georgakilas, A.G., Martin, O.A. and Bonner, W.M. (2017) p21: A Two-Faced Genome Guardian. Trends Mol Med, 23, 310-319.
  6. Nikitaki, Z., Nikolov, V., Mavragani, I.V., Mladenov, E., Mangelis, A., Laskaratou, D.A., Fragkoulis, G.I., Hellweg, C.E., Martin, O.A., Emfietzoglou, D. et al. (2016) Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET). Free Radic Res, 50, S64-S78.
  7. Nikitaki, Z., Mavragani, I.V., Laskaratou, D.A., Gika, V., Moskvin, V.P., Theofilatos, K., Vougas, K., Stewart, R.D. and Georgakilas, A.G. (2016) Systemic mechanisms and effects of ionizing radiation: A new ‘old’ paradigm of how the bystanders and distant can become the players. Semin Cancer Biol, 37-38, 77-95.
  8. Bignon, E., Gattuso, H., Morell, C., Dehez, F., Georgakilas, A.G., Monari, A. and Dumont, E. (2016) Correlation of bistranded clustered abasic DNA lesion processing with structural and dynamic DNA helix distortion. Nucleic Acids Res, 44, 8588-8599.
  9. Pateras, I.S., Havaki, S., Nikitopoulou, X., Vougas, K., Townsend, P.A., Panayiotidis, M.I., Georgakilas, A.G. and Gorgoulis, V.G. (2015) The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where.Pharmacol Ther, 154, 36-56.
  10. Nikitaki, Z., Hellweg, C.E., Georgakilas, A.G. and Ravanat, J.L. (2015) Stress-induced DNA damage biomarkers: applications and limitations. Frontiers in chemistry, 3, 35.
  11. Hatzi, V.I., Laskaratou, D.A., Mavragani, I.V., Nikitaki, Z., Mangelis, A., Panayiotidis, M.I., Pantelias, G.E., Terzoudi, G.I. and Georgakilas, A.G. (2015) Non-targeted radiation effects in vivo: A critical glance of the future in radiobiology. Cancer Lett, 356, 34-42.
  12. Georgakilas, A.G., O’Neill, P. and Stewart, R.D. (2013) Induction and repair of clustered DNA Lesions: What do we know so far? Radiat. Res., 180, 100–109.

Recent publications

2020

  1. Kanakoglou DS, Michalettou TD, Vasileiou C, Gioukakis E, Maneta D, Kyriakidis KV, Georgakilas AG, Michalopoulos I. (2020)  Effects of High-Dose Ionizing Radiation in Human Gene Expression: A Meta-Analysis. International Journal of  Molecular Sciences. 21(6)
  2. Dilucca M, Pavlopoulou A,Georgakilas AG, Giansanti A. (2020) Codon usage bias in radioresistant bacteria. Gene:144554. doi: 10.1016/j.gene.2020.144554.
  3. Margis S, Magouni M, Kyriakou I,Georgakilas AG, Incerti S, Emfietzoglou D. (2020) Microdosimetric calculations of the direct DNA damage induced by low energy electrons using the Geant4-DNA Monte Carlo code. Physics in Medicine and Biology. 65(4)

2019

  1. Ventura, J., Sprung, C.N., Forrester, H.B., Palazzolo, J.S., Ivashkevich, A., Stevenson, A.W., Hall, C.J., Georgakilas, A.G., Lobachevsky, P.N. and Martin, O.A. (2019) Micro-Mini & Nano Dosimetry (MMND) 2018, 6–11 February 2018, Mooloolaba, Queensland, Australia: Systemic effects of synchrotron radiation. Journal of Physics: Conference Series, 1154, 012028.
  2. Lobachevsky, P.N., Ventura, J., Giannakandropoulou, L., Forrester, H., Palazzolo, J.S., Haynes, N.M., Stevenson, A.W., Hall, C.J., Mason, J., Pollakis, G. et al. (2019) A Functional Immune System Is Required For The Systemic Genotoxic Effects Of Localised Irradiation. International Journal of Radiation Oncology*Biology*Physics, 103 1184-1193.
  3. Dimitriou, N.M., Pavlopoulou, A., Tremi, I., Kouloulias, V., Tsigaridas, G. and Georgakilas, A.G. (2019) Prediction of Gold Nanoparticle and Microwave-Induced Hyperthermia Effects on Tumor Control via a Simulation Approach. Nanomaterials, 9, 167-186.
  4. Toy, H.I., Okmen, D., Kontou, P.I., Georgakilas, A.G. and Pavlopoulou, A. (2019) HOTAIR as a Prognostic Predictor for Diverse Human Cancers: A Meta- and Bioinformatics Analysis. Cancers, 11, 778.
  5. Pavlopoulou, A., Karaca, E., Balestrazzi, A. and Georgakilas, A.G. (2019) In Silico Phylogenetic and Structural Analyses of Plant Endogenous Danger Signaling Molecules upon Stress. Oxidative Medicine and Cellular Longevity, 2019, 14.
  6. Pantelias, A., Karachristou, I., Georgakilas, A.G. and Terzoudi, G.I. (2019) Interphase Cytogenetic Analysis of Micronucleated and Multinucleated Cells Supports the Premature Chromosome Condensation Hypothesis as the Mechanistic Origin of Chromothripsis. Cancers, 11, 1123.
  7. Myrianthopoulos, V., Evangelou, K., Vasileiou, P.V.S., Cooks, T., Vassilakopoulos, T.P., Pangalis, G.A., Kouloukoussa, M., Kittas, C., Georgakilas, A.G. and Gorgoulis, V.G. (2019) Senescence and senotherapeutics: a new field in cancer therapy. Pharmacology & Therapeutics, 193, 31-49.
  8. Mavragani, I.V., Nikitaki, Z., Kalospyros, S.A. and Georgakilas, A.G. (2019) Ionizing Radiation and Complex DNA Damage: From Prediction to Detection Challenges and Biological Significance. Cancers, 11, 1789.
  9. Düzgün , M.B., Theofilatos, K., Georgakilas, A.G. and Pavlopoulou, A. (2019) A Bioinformatic Approach for the Identification of Molecular Determinants of Resistance/Sensitivity to Cancer Thermotherapy. Oxidative Medicine and Cellular Longevity, 2019, 13.

 

2018

  1. Ventura, J., Lobachevsky, P., Palazzolo, J., Forrester, H., Haynes, N., Ivashkevich, A., Stevenson, A., Hall, C., Gorgoulis, V., Hamilton, J. et al. (2018) Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. Abstract 4573: Localized synchrotron radiation in mice induces persistent systemic genotoxic events mediated by the functional immune system. Cancer Research, 78, 4573.
  2. Tremi, I., Anagnostopoulos, D., Spyratou, E., Gkeka, P., Georgakilas, A.G., Chatgilialoglu, C. and Cournia, Z. (2018) Effect of 5-trans Isomer of Arachidonic Acid on Model Liposomal Membranes Studied by a Combined Simulation and Experimental Approach. The Journal of membrane biology, 251, 475-489.
  3. Pouget, J.P., Georgakilas, A.G. and Ravanat, J.L. (2018) Targeted and Off-Target (Bystander and Abscopal) Effects of Radiation Therapy: Redox Mechanisms and Risk-Benefit Analysis. Antioxid Redox Signal.
  4. Nikolaou, M., Pavlopoulou, A., Georgakilas, A.G. and Kyrodimos, E. (2018) The challenge of drug resistance in cancer treatment: a current overview. Clinical & experimental metastasis.
  5. Nikitaki, Z., Hola, M., Dona, M., Pavlopoulou, A., Michalopoulos, I., Angelis, K.J., Georgakilas, A.G., Macovei, A. and Balestrazzi, A. (2018) Integrating plant and animal biology for the search of novel DNA damage biomarkers. Mutat Res, 775, 21-38.
  6. Myrianthopoulos, V., Evangelou, K., Vasileiou, P.V.S., Cooks, T., Vassilakopoulos, T.P., Pangalis, G.A., Kouloukoussa, M., Kittas, C., Georgakilas, A.G. and Gorgoulis, V.G. (2018) Senescence and senotherapeutics: a new field in cancer therapy. Pharmacol Ther.
  7. Katsiki, A., Karatzas, P., Georgakilas, A.G. and C., V. (2018), Poster presentation at: ECCB18 – 17th European Conference on Computational biology; 2018 Sep 8-12; Athens, Greece.
  8. Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N.N., Glytsou, C., Pateras, I.S., Swain, U., Souliotis, V.L. et al. (2018) Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biology, 19, 37.
  9. Fragopoulou, A.F., Polyzos, A., Papadopoulou, M.D., Sansone, A., Manta, A.K., Balafas, E., Kostomitsopoulos, N., Skouroliakou, A., Chatgilialoglu, C., Georgakilas, A. et al. (2018) Hippocampal lipidome and transcriptome profile alterations triggered by acute exposure of mice to GSM 1800 MHz mobile phone radiation: An exploratory study. Brain and behavior, 8, e01001.180, 100–109.