Key Publications
- Lobachevsky, P.N., Ventura, J., Giannakandropoulou, L., Forrester, H., Palazzolo, J.S., Haynes, N.M., Stevenson, A.W., Hall, C.J., Mason, J., Pollakis, G. et al. (2019) A Functional Immune System Is Required For The Systemic Genotoxic Effects Of Localised Irradiation. International Journal of Radiation Oncology*Biology*Physics, 103 1184-1193.
- Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N.N., Glytsou, C., Pateras, I.S., Swain, U., Souliotis, V.L. et al. (2018) Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biology, 19, 37.
- Ventura, J., Lobachevsky, P.N., Palazzolo, J.S., Forrester, H., Haynes, N.M., Ivashkevich, A., Stevenson, A.W., Hall, C.J., Ntargaras, A., Kotsaris, V. et al. (2017) Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses. Cancer Res, 77, 6389-6399.
- Pavlopoulou, A., Bagos, P.G., Koutsandrea, V. and Georgakilas, A.G. (2017) Molecular determinants of radiosensitivity in normal and tumor tissue: A bioinformatic approach. Cancer Lett, 403, 37-47. Mavragani, I., Nikitaki, Z., Souli, M., Aziz, A., Nowsheen, S., Aziz, K., Rogakou, E. and Georgakilas, A. (2017) Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis. Cancers, 9, 91.
- Georgakilas, A.G., Martin, O.A. and Bonner, W.M. (2017) p21: A Two-Faced Genome Guardian. Trends Mol Med, 23, 310-319.
- Nikitaki, Z., Nikolov, V., Mavragani, I.V., Mladenov, E., Mangelis, A., Laskaratou, D.A., Fragkoulis, G.I., Hellweg, C.E., Martin, O.A., Emfietzoglou, D. et al. (2016) Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET). Free Radic Res, 50, S64-S78.
- Nikitaki, Z., Mavragani, I.V., Laskaratou, D.A., Gika, V., Moskvin, V.P., Theofilatos, K., Vougas, K., Stewart, R.D. and Georgakilas, A.G. (2016) Systemic mechanisms and effects of ionizing radiation: A new ‘old’ paradigm of how the bystanders and distant can become the players. Semin Cancer Biol, 37-38, 77-95.
- Bignon, E., Gattuso, H., Morell, C., Dehez, F., Georgakilas, A.G., Monari, A. and Dumont, E. (2016) Correlation of bistranded clustered abasic DNA lesion processing with structural and dynamic DNA helix distortion. Nucleic Acids Res, 44, 8588-8599.
- Pateras, I.S., Havaki, S., Nikitopoulou, X., Vougas, K., Townsend, P.A., Panayiotidis, M.I., Georgakilas, A.G. and Gorgoulis, V.G. (2015) The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where.Pharmacol Ther, 154, 36-56.
- Nikitaki, Z., Hellweg, C.E., Georgakilas, A.G. and Ravanat, J.L. (2015) Stress-induced DNA damage biomarkers: applications and limitations. Frontiers in chemistry, 3, 35.
- Hatzi, V.I., Laskaratou, D.A., Mavragani, I.V., Nikitaki, Z., Mangelis, A., Panayiotidis, M.I., Pantelias, G.E., Terzoudi, G.I. and Georgakilas, A.G. (2015) Non-targeted radiation effects in vivo: A critical glance of the future in radiobiology. Cancer Lett, 356, 34-42.
- Georgakilas, A.G., O’Neill, P. and Stewart, R.D. (2013) Induction and repair of clustered DNA Lesions: What do we know so far? Radiat. Res., 180, 100–109.
Recent publications
2020
- Kanakoglou DS, Michalettou TD, Vasileiou C, Gioukakis E, Maneta D, Kyriakidis KV, Georgakilas AG, Michalopoulos I. (2020) Effects of High-Dose Ionizing Radiation in Human Gene Expression: A Meta-Analysis. International Journal of Molecular Sciences. 21(6)
- Dilucca M, Pavlopoulou A,Georgakilas AG, Giansanti A. (2020) Codon usage bias in radioresistant bacteria. Gene:144554. doi: 10.1016/j.gene.2020.144554.
- Margis S, Magouni M, Kyriakou I,Georgakilas AG, Incerti S, Emfietzoglou D. (2020) Microdosimetric calculations of the direct DNA damage induced by low energy electrons using the Geant4-DNA Monte Carlo code. Physics in Medicine and Biology. 65(4)
2019
- Ventura, J., Sprung, C.N., Forrester, H.B., Palazzolo, J.S., Ivashkevich, A., Stevenson, A.W., Hall, C.J., Georgakilas, A.G., Lobachevsky, P.N. and Martin, O.A. (2019) Micro-Mini & Nano Dosimetry (MMND) 2018, 6–11 February 2018, Mooloolaba, Queensland, Australia: Systemic effects of synchrotron radiation. Journal of Physics: Conference Series, 1154, 012028.
- Lobachevsky, P.N., Ventura, J., Giannakandropoulou, L., Forrester, H., Palazzolo, J.S., Haynes, N.M., Stevenson, A.W., Hall, C.J., Mason, J., Pollakis, G. et al. (2019) A Functional Immune System Is Required For The Systemic Genotoxic Effects Of Localised Irradiation. International Journal of Radiation Oncology*Biology*Physics, 103 1184-1193.
- Dimitriou, N.M., Pavlopoulou, A., Tremi, I., Kouloulias, V., Tsigaridas, G. and Georgakilas, A.G. (2019) Prediction of Gold Nanoparticle and Microwave-Induced Hyperthermia Effects on Tumor Control via a Simulation Approach. Nanomaterials, 9, 167-186.
- Toy, H.I., Okmen, D., Kontou, P.I., Georgakilas, A.G. and Pavlopoulou, A. (2019) HOTAIR as a Prognostic Predictor for Diverse Human Cancers: A Meta- and Bioinformatics Analysis. Cancers, 11, 778.
- Pavlopoulou, A., Karaca, E., Balestrazzi, A. and Georgakilas, A.G. (2019) In Silico Phylogenetic and Structural Analyses of Plant Endogenous Danger Signaling Molecules upon Stress. Oxidative Medicine and Cellular Longevity, 2019, 14.
- Pantelias, A., Karachristou, I., Georgakilas, A.G. and Terzoudi, G.I. (2019) Interphase Cytogenetic Analysis of Micronucleated and Multinucleated Cells Supports the Premature Chromosome Condensation Hypothesis as the Mechanistic Origin of Chromothripsis. Cancers, 11, 1123.
- Myrianthopoulos, V., Evangelou, K., Vasileiou, P.V.S., Cooks, T., Vassilakopoulos, T.P., Pangalis, G.A., Kouloukoussa, M., Kittas, C., Georgakilas, A.G. and Gorgoulis, V.G. (2019) Senescence and senotherapeutics: a new field in cancer therapy. Pharmacology & Therapeutics, 193, 31-49.
- Mavragani, I.V., Nikitaki, Z., Kalospyros, S.A. and Georgakilas, A.G. (2019) Ionizing Radiation and Complex DNA Damage: From Prediction to Detection Challenges and Biological Significance. Cancers, 11, 1789.
- Düzgün , M.B., Theofilatos, K., Georgakilas, A.G. and Pavlopoulou, A. (2019) A Bioinformatic Approach for the Identification of Molecular Determinants of Resistance/Sensitivity to Cancer Thermotherapy. Oxidative Medicine and Cellular Longevity, 2019, 13.
2018
- Ventura, J., Lobachevsky, P., Palazzolo, J., Forrester, H., Haynes, N., Ivashkevich, A., Stevenson, A., Hall, C., Gorgoulis, V., Hamilton, J. et al. (2018) Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. Abstract 4573: Localized synchrotron radiation in mice induces persistent systemic genotoxic events mediated by the functional immune system. Cancer Research, 78, 4573.
- Tremi, I., Anagnostopoulos, D., Spyratou, E., Gkeka, P., Georgakilas, A.G., Chatgilialoglu, C. and Cournia, Z. (2018) Effect of 5-trans Isomer of Arachidonic Acid on Model Liposomal Membranes Studied by a Combined Simulation and Experimental Approach. The Journal of membrane biology, 251, 475-489.
- Pouget, J.P., Georgakilas, A.G. and Ravanat, J.L. (2018) Targeted and Off-Target (Bystander and Abscopal) Effects of Radiation Therapy: Redox Mechanisms and Risk-Benefit Analysis. Antioxid Redox Signal.
- Nikolaou, M., Pavlopoulou, A., Georgakilas, A.G. and Kyrodimos, E. (2018) The challenge of drug resistance in cancer treatment: a current overview. Clinical & experimental metastasis.
- Nikitaki, Z., Hola, M., Dona, M., Pavlopoulou, A., Michalopoulos, I., Angelis, K.J., Georgakilas, A.G., Macovei, A. and Balestrazzi, A. (2018) Integrating plant and animal biology for the search of novel DNA damage biomarkers. Mutat Res, 775, 21-38.
- Myrianthopoulos, V., Evangelou, K., Vasileiou, P.V.S., Cooks, T., Vassilakopoulos, T.P., Pangalis, G.A., Kouloukoussa, M., Kittas, C., Georgakilas, A.G. and Gorgoulis, V.G. (2018) Senescence and senotherapeutics: a new field in cancer therapy. Pharmacol Ther.
- Katsiki, A., Karatzas, P., Georgakilas, A.G. and C., V. (2018), Poster presentation at: ECCB18 – 17th European Conference on Computational biology; 2018 Sep 8-12; Athens, Greece.
- Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N.N., Glytsou, C., Pateras, I.S., Swain, U., Souliotis, V.L. et al. (2018) Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biology, 19, 37.
- Fragopoulou, A.F., Polyzos, A., Papadopoulou, M.D., Sansone, A., Manta, A.K., Balafas, E., Kostomitsopoulos, N., Skouroliakou, A., Chatgilialoglu, C., Georgakilas, A. et al. (2018) Hippocampal lipidome and transcriptome profile alterations triggered by acute exposure of mice to GSM 1800 MHz mobile phone radiation: An exploratory study. Brain and behavior, 8, e01001.180, 100–109.